What Are The Symptoms Of Lynch Syndrome? How is Lynch Syndrome Treated?, How is Lynch Syndrome cured? Some information you need to know about it.
What Are The Symptoms Of Lynch Syndrome? How is Lynch Syndrome Treated?
Lynch syndrome, also called non-polyposis non-hereditary colorectal cancer, is the most common form of hereditary colorectal cancer. The diagnosis of this syndrome can be made by clinical findings, pathological features, family history and genetic tests. In the content of our article, you can find detailed answers to the questions causes of Lynch syndrome and How is Lynch syndrome treated? that we have prepared for you, our valued friends. So What are the symptoms of Lynch syndrome?
Individuals with Lynch syndrome also have cancer of the small intestine, stomach, liver, gallbladder ducts, urinary tract, brain and skin. Women with Lynch syndrome have a higher risk of developing cancer than men with this condition. In people with Lynch syndrome, cancer usually starts after the age of 40 or 50. Individuals with Lynch syndrome generally have a higher risk of developing colon cancer before the age of 50. Symptoms include a family history of other cancers that cause this disease, including kidney cancer, pancreatic cancer, brain cancer, stomach cancer, bladder cancer, small intestine cancer, ureter cancer, gallbladder cancer, bile duct cancer and skin cancer.
Lynch syndrome, which can be transferred from person to person due to genetic reasons, is more common after the age of 40. Mutations that cause this condition cause defects in the DNA mismatch repair genes, which enable DNA to repair itself. Genes associated with Lynch syndrome that play a role in DNA mismatch repair are listed as MLH1, MLH2, PMS2 and EPCAM. Any mutation in these genes puts the individual at an increased lifetime risk of developing colorectal cancer, endometrial cancer, ovarian cancer and other related cancers. Individuals with Lynch syndrome have different risks for various types of cancer, depending on the mutation in their body. Although variants in these genes predispose individuals to cancer, not all individuals with these variants develop cancerous tumors. You can find detailed information about Lynch syndrome symptoms by continuing our article.
How is Lynch Syndrome Treated?
Lynch Syndrome Symptoms
– Nausea or vomiting,
– Abdominal pain or cramps,
– Constipation,
– Seeing blood in the stool,
– Diarrhea,
– General fatigue and weakness,
– Anemia,
– Excessive bloating and gas,
– Fast weight loss.
What Cancers Does Lynch Syndrome Cause?
– Ovarian cancer; 1% to 40%
– Endometrial cancer; 15% to 60%
– Brain or central nervous system tumor; 1% to 5%
– Hepatobiliary system cancer; 1% to 5%
– Urinary tract cancer; 1% to 20%
– Stomach cancer; 1% to 15%
– Pancreatic cancer; 1% to 7%
– Small intestine cancer; 1% to 7%
– Colorectal cancer; 20% to 80%
Lynch syndrome can be diagnosed by testing by taking a DNA sample from the individual’s blood or saliva. This test determines whether a person carries a transmissible mutation in one of the genes associated with Lynch syndrome. Tests are available for the MLH1, MSH2, MSH6, PMS2 and EPCAM genes. In addition, screening tests can be performed on cancerous tissue in Lynch syndrome. As a result of these tests, it can be seen whether the cancer is genetic or hereditary. Planning for Lynch syndrome treatment develops after the detection of cancer in the body. The specialist physician can focus on removing this type of cancer from the body through surgical intervention. In cases where the type of cancer occurring in the individual is the large intestine, it is recommended to remove the entire intestine through surgical intervention. In case of early diagnosis, treatment is shaped accordingly and the rate of recovery increases. If the diagnosis is made in the late stages, the chance of recovery may drop to 50% or below.
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